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The myelin membrane is composed of proteins (20--30%) and lipids (70-80%). Although the amount of lipid on a weight basis exceeds that of protein by a factor of 3-4, the propertics of the membrane are not determined solely by the amount of

Abbreviation: DIDS, 4, 4'-diisothiocyano-2, 2'-ditritiostilbene disulfonic acid. Charged amino acids (pH 7.4): Asp, Asn, Glu, Gin, Lys, Arg. Neutral polar amino acids: Thr, Ser, Tyr Neutral apolar amino acids (pH 7.4): Pro, His, Gly. Hydrophobic amino acids: Ala, Val, Cys, Met, He, Lcu, Phe, Trp.