作者
Won Se Suh, Ki Hyun Kim, Ho Kyung Kim, Sang Un Choi, Kang Ro Lee
发表日期
2015/8
期刊
Helvetica Chimica Acta
卷号
98
期号
8
页码范围
1087-1094
出版商
WILEY‐VCH Verlag
简介
Two new aryl‐tetralin lignan glycosides, linderanosides A and B (1 and 2, resp.), and a new dihydrobenzofuran neolignan glycoside, linderanoside C (3), together with five known lignan derivatives (48) were isolated from the trunk of Lindera glauca. The structures of these new compounds were determined through spectroscopic analyses, including extensive 2D‐NMR data and acid hydrolysis. The absolute configurations of the compounds were clarified by circular dichroism (CD) spectroscopic studies. Compounds 18 were evaluated for their cytotoxicity against A549 (non‐small cell lung adenocarcinoma), SK‐OV‐3 (ovarian cancer cells), A498 (human kidney epithelial cells), and HCT‐15 (colon cancer cells) human tumor cell lines using sulforhodamine B assays in vitro.
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