作者
Rezan Abdul‐Kadir, Claire McLintock, Anne‐Sophie Ducloy, Hazem El‐Refaey, Adrian England, Augusto B Federici, Chad A Grotegut, Susan Halimeh, Jay H Herman, Stefan Hofer, Andra H James, Peter A Kouides, Michael J Paidas, Flora Peyvandi, Rochelle Winikoff
发表日期
2014/7
来源
Transfusion
卷号
54
期号
7
页码范围
1756-1768
简介
Background
Postpartum hemorrhage (PPH) remains one of the leading causes of maternal morbidity and mortality worldwide, although the lack of a precise definition precludes accurate data of the absolute prevalence of PPH.
Study Design and Methods
An international expert panel in obstetrics, gynecology, hematology, transfusion, and anesthesiology undertook a comprehensive review of the literature. At a meeting in November 2011, the panel agreed on a definition of severe PPH that would identify those women who were at a high risk of adverse clinical outcomes.
Results
The panel agreed on the following definition for severe persistent (ongoing) PPH: “Active bleeding >1000 mL within the 24 hours following birth that continues despite the use of initial measures including first‐line uterotonic agents and uterine massage.” A treatment algorithm for severe persistent PPH was subsequently developed. Initial …
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