作者
Mauro Panigada, Nicola Bottino, Paola Tagliabue, Giacomo Grasselli, Cristina Novembrino, Veena Chantarangkul, Antonio Pesenti, Flora Peyvandi, Armando Tripodi
发表日期
2020/7
期刊
Journal of thrombosis and haemostasis
卷号
18
期号
7
页码范围
1738-1742
简介
Background
The severe inflammatory state secondary to COVID‐19 leads to a severe derangement of hemostasis that has been recently described as a state of disseminated intravascular coagulation (DIC) and consumption coagulopathy, defined as decreased platelet count, increased fibrin(ogen) degradation products such as D‐dimer, as well as low fibrinogen.
Aims
Whole blood from 24 patients admitted at the intensive care unit because of COVID‐19 was collected and evaluated with thromboelastography by the TEG point‐of‐care device on a single occasion and six underwent repeated measurements on two consecutive days for a total of 30 observations. Plasma was evaluated for the other parameters of hemostasis.
Results
TEG parameters are consistent with a state of hypercoagulability as shown by decreased values, and increased values of K angle and MA. Platelet count was normal or increased …
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