作者
Harsha L Rao, Linda M Zangwill, Robert N Weinreb, Pamela A Sample, Luciana M Alencar, Felipe A Medeiros
发表日期
2010/9/1
期刊
Ophthalmology
卷号
117
期号
9
页码范围
1692-1699. e1
出版商
Elsevier
简介
PURPOSE
To evaluate retinal nerve fiber layer (RNFL), optic nerve head (ONH), and macular thickness measurements for glaucoma detection using the RTVue spectral domain optical coherence tomograph.
DESIGN
Diagnostic, case-control study.
PARTICIPANTS
One hundred forty eyes of 106 glaucoma patients and 74 eyes of 40 healthy subjects from the Diagnostic Innovations in Glaucoma Study (DIGS).
METHODS
All patients underwent ocular imaging with the commercially available RTVue. Optic nerve head, RNFL thickness, and macular thickness scans were obtained during the same visit. Receiver operating characteristic (ROC) curves and sensitivities at fixed specificities (80% and 95%) were calculated for each parameter.
MAIN OUTCOME MEASURES
Areas under the ROC curves (AUC) and sensitivities at fixed specificities of 80% and 95%.
RESULTS
The AUC for the RNFL parameter with best …
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