作者
Adeleh Yarmohammadi, Linda M Zangwill, Alberto Diniz-Filho, Min Hee Suh, Siamak Yousefi, Luke J Saunders, Akram Belghith, Patricia Isabel C Manalastas, Felipe A Medeiros, Robert N Weinreb
发表日期
2016/12/1
期刊
Ophthalmology
卷号
123
期号
12
页码范围
2498-2508
出版商
Elsevier
简介
Purpose
To evaluate the association between vessel density measurements using optical coherence tomography angiography (OCT-A) and severity of visual field loss in primary open-angle glaucoma.
Design
Observational, cross-sectional study.
Participants
A total of 153 eyes from 31 healthy participants, 48 glaucoma suspects, and 74 glaucoma patients enrolled in the Diagnostic Innovations in Glaucoma Study.
Methods
All eyes underwent imaging using OCT-A (Angiovue; Optovue, Fremont, CA), spectral-domain OCT (Avanti; Optovue), and standard automated perimetry (SAP). Retinal vasculature information was summarized as vessel density, the percentage of area occupied by flowing blood vessels in the selected region. Two measurements from the retinal nerve fiber layer (RNFL) were used: circumpapillary vessel density (cpVD) (750-μm-wide elliptical annulus around the optic disc) and whole-image vessel …
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