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This chapter emphasizes the role of lipid-based nanoparticles and their characteristics, which helps them to become an appropriate candidate to be considered for the treatment of different types of cancer. The pharmaceutical development of the formulations will be facilitated by gaining a higher understanding and increasing the number of nanosystems based on lipids to achieve a higher reach in the market. Cancer is a condition in which a few of the body’s cells grow out of control and migrate to other body regions. Cancer is a hereditary disease, meaning that genetic abnormalities that affect how our cells function—particularly how they grow and divide—cause cancer. Scientists have discovered that specific mutations frequently occur in various cancer forms as they learn more about the molecular alterations that cause cancer. Precision therapy has been developed due to the introduction of targeted therapy …