查看文章

Morphometry of brain structures based on magnetic resonance imaging (MRI) data has become an important tool in neurobiology. Recent multicenter studies in neurodegenerative diseases raised the issue of the precision of volumetric measures, and their dependence on the scanner properties and imaging protocol. A large dataset consisting of 1073 MRI examinations in 843 subjects, acquired on 90 scanners at 58 sites, is analyzed here. A comprehensive set of image quality and content measures is used to describe the influence of the scanner hardware and imaging protocol on the variability of morphometric measures. Scanners equipped with array coils show a remarkable advantage over conventional coils in terms of image quality measures. The signal- and contrast-to-noise ratio in similar systems is equal or slightly better at 1.5 T than 3.0 T, while the white/grey matter tissue contrast is generally better on …