作者
Mohammad Javed Ansari, Ahmad Al-Ghamdi, Salma Usmani, Noori S Al-Waili, Deepak Sharma, Adgaba Nuru, Yehya Al-Attal
发表日期
2013/7/16
期刊
Archives of Medical Research
出版商
Elsevier
简介
Background and Aims
Candida species, especially Candida albicans, are major fungal pathogens of humans that are capable of causing superficial mucosal infections and systemic infections in humans. The aim of this study was to evaluate the jujube (Zizyphus spina-christi) honey for its in vitro inhibitory activity against pre-formed biofilm and its interference with the biofilm formation of C. albicans.
Methods
The XTT reduction assay, scanning electron microscopy (SEM) and atomic force microscopy (AFM) were employed to determine the inhibitory effect of Jujube honey on C. albicans biofilm. Changes in the infrared spectrum after treatment with honey were also determined by Fourier transform infrared (FTIR) spectroscopy.
Results
Jujube honey affects biofilms by decreasing the size of mature biofilms and by disruption of their structure. At a concentration of 40% w/v, it interferes with formation of C. albicans biofilms …
学术搜索中的文章
MJ Ansari, A Al-Ghamdi, S Usmani, NS Al-Waili… - Archives of medical research, 2013