作者
Sam Parnia, Jie Yang, Robert Nguyen, Anna Ahn, Jiawen Zhu, Loren Inigo-Santiago, Asad Nasir, Kim Golder, Shreyas Ravishankar, Pauline Bartlett, Jianjin Xu, David Pogson, Sarah Cooke, Christopher Walker, Ken Spearpoint, David Kitson, Teresa Melody, Mehboob Chilwan, Elinor Schoenfeld, Paul Richman, Barbara Mills, Nancy Wichtendahl, Jerry Nolan, Adam Singer, Stephen Brett, Gavin D Perkins, Charles D Deakin
发表日期
2016/9/1
期刊
Critical care medicine
卷号
44
期号
9
页码范围
1663-1674
出版商
LWW
简介
Objectives: Cardiac arrest is associated with morbidity and mortality because of cerebral ischemia. Therefore, we tested the hypothesis that higher regional cerebral oxygenation during resuscitation is associated with improved return of spontaneous circulation, survival, and neurologic outcomes at hospital discharge. We further examined the validity of regional cerebral oxygenation as a test to predict these outcomes.
Design: Multicenter prospective study of in-hospital cardiac arrest.
Setting: Five medical centers in the United States and the United Kingdom.
Patients: Inclusion criteria are as follows: in-hospital cardiac arrest, age 18 years old or older, and prolonged cardiopulmonary resuscitation greater than or equal to 5 minutes. Patients were recruited consecutively during working hours between August 2011 and September 2014. Survival with a favorable neurologic outcome was defined as a cerebral …
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S Parnia, J Yang, R Nguyen, A Ahn, J Zhu… - Critical care medicine, 2016