作者
Sung-Bum Kang, Jung Rae Cho, Seung-Yong Jeong, Jae Hwan Oh, Soyeon Ahn, Sunkyu Choi, Duck-Woo Kim, Bong Hwa Lee, Eui Gon Youk, Sung Chan Park, Seung Chul Heo, Doo-Seok Lee, Seung-Bum Ryoo, Ji Won Park, Hyoung-Chul Park, Sung-Min Lee, Sung Il Kang, Min Hyun Kim, Heung-Kwon Oh, Rumi Shin, Min Jung Kim, Kyoung Ho Lee, Young-Hoon Kim, Jae-Sung Kim, Keun-Wook Lee, Hye Seung Lee, Hyun Jung Kim, Young Soo Park, Dae Kyung Sohn, Kyu Joo Park
发表日期
2021/1/1
期刊
The Lancet Regional Health–Western Pacific
卷号
6
出版商
Elsevier
简介
Background
The long-term effects of radical resection on quality of life may influence the treatment selection. The objective of this study was to determine whether abdominoperineal resection has a better effect on the quality of life than sphincter preservation surgery at 3 years after surgery
Methods
This prospective, cohort study included patients who underwent radical resection for low rectal cancer. The primary outcomes were European Organisation for Research and Treatment of Cancer QLQ-C30 and CR38 quality of life scores 3 years after surgery, which were compared with linear generalised estimating equations, after adjustment for baseline values, a time effect, and an interaction effect between time and treatment. The secondary outcomes included sexual-urinary functions and oncological outcomes. The study was registered with ClinicalTrials.gov (NCT01461525).
Findings
Between December 2011 and …
学术搜索中的文章
SB Kang, JR Cho, SY Jeong, JH Oh, S Ahn, S Choi… - The Lancet Regional Health–Western Pacific, 2021