作者
Lara A Ray, Erica N Grodin, Lorenzo Leggio, Anita J Bechtholt, Howard Becker, Sarah W Feldstein Ewing, James David Jentsch, Andrea C King, Barbara J Mason, Stephanie O'Malley, James MacKillop, Markus Heilig, George F Koob
发表日期
2021/3
期刊
Addiction biology
卷号
26
期号
2
页码范围
e12903
简介
In March 2019, a scientific meeting was held at the University of California, Los Angeles (UCLA) Luskin Center to discuss approaches to expedite the translation of neurobiological insights to advances in the treatment of alcohol use disorder (AUD). A guiding theme that emerged was that while translational research in AUD is clearly a challenge, it is also a field ripe with opportunities. Herein, we seek to summarize and disseminate the recommendations for the future of translational AUD research using four sections. First, we briefly review the current landscape of AUD treatment including the available evidence‐based treatments and their uptake in clinical settings. Second, we discuss AUD treatment development efforts from a translational science viewpoint. We review current hurdles to treatment development as well as opportunities for mechanism‐informed treatment. Third, we consider models of translational …
引用总数
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LA Ray, EN Grodin, L Leggio, AJ Bechtholt, H Becker… - Addiction biology, 2021