作者
Omar F Ammar, Kashish Sharma, George Liperis, Juan J Fraire-Zamora, Munevver Serdarogullari, Zoya E Ali, Ranjith Ramasamy, Sandra Laurentino, Adam Watkins, Mina Mincheva
发表日期
2023/8/1
期刊
Human Reproduction
卷号
38
期号
8
页码范围
1649-1653
出版商
Oxford University Press
简介
The term ‘obesity’refers to an excessive amount of fat accumulating within the body and a high BMI 30 and has been linked to a range of chronic diseases, including cardiovascular diseases and cancer (WHO, 2021). The surge in obesity rates has coincided with a steady decline in sperm quality, particularly sperm counts reported over the last 50 years (Levine et al., 2017, 2023). The various processes involved in reproduction, such as hormone production, gametogenesis, fertilization, and embryo development, can be adversely affected by obesity and its associated metabolic disorders. Data from animal studies strongly indicate that high-fat diet-induced obesity and its associated metabolic disease negatively affect fertility and reproduction (Pini et al., 2021). There is a lack of data about the link between obesity and human reproduction due to the complicated interactions between obesity, dyslipidaemia …
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