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Background:

Long-term exposure to fine particulate matter (PM with an aerodynamic diameter≤ 2.5 µm; PM 2.5) contributes to an elevated incidence of type 2 diabetes (T2D) in North America and Europe, but there is limited empirical evidence for Asian countries. This study determined the association between and the exposure-response relationship for PM 2.5 and the incidence of T2D in Taiwan.

Methods:

This retrospective cohort study was conducted for the years 2001–2012. Health information, including age, sex, health insurance premium, type of occupation, medication, and disease status, was retrieved from the Longitudinal Health Insurance Database 2000. Monitoring data for PM 2.5 came from the Environmental Protection Administration of Taiwan, and Land-use Regression modeling was used to approximate participants’ long-term exposure to PM 2.5. Cox proportional hazards models with a generalized …