作者
Dale L Boger, Jeffrey A McKie, Christopher W Boyce
发表日期
1997/6
期刊
Synlett
卷号
1997
期号
Sup. I
页码范围
515-517
出版商
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.
简介
Two exceptionally short and effective asymmetric syntheses of N-BOC-CBI are detailed based on an asymmetric hydroboration (80% ee) or Jacobsen epoxidation (92% ee) of a 3, 4-dihydrobenzo [f] quinoline followed by direct, transannular spirocyclization for introduction of the activated cyclopropane.
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DL Boger, JA McKie, CW Boyce - Synlett, 1997