作者
Frank AW Coumans, Alain R Brisson, Edit I Buzas, Françoise Dignat-George, Esther EE Drees, Samir El-Andaloussi, Costanza Emanueli, Aleksandra Gasecka, An Hendrix, Andrew F Hill, Romaric Lacroix, Yi Lee, Ton G Van Leeuwen, Nigel Mackman, Imre Mäger, John P Nolan, Edwin Van Der Pol, D Michiel Pegtel, Susmita Sahoo, Pia RM Siljander, Guus Sturk, Olivier De Wever, Rienk Nieuwland
发表日期
2017/5/12
来源
Circulation research
卷号
120
期号
10
页码范围
1632-1648
出版商
Lippincott Williams & Wilkins
简介
Owing to the relationship between extracellular vesicles (EVs) and physiological and pathological conditions, the interest in EVs is exponentially growing. EVs hold high hopes for novel diagnostic and translational discoveries. This review provides an expert-based update of recent advances in the methods to study EVs and summarizes currently accepted considerations and recommendations from sample collection to isolation, detection, and characterization of EVs. Common misconceptions and methodological pitfalls are highlighted. Although EVs are found in all body fluids, in this review, we will focus on EVs from human blood, not only our most complex but also the most interesting body fluid for cardiovascular research.
学术搜索中的文章
FAW Coumans, AR Brisson, EI Buzas, F Dignat-George… - Circulation research, 2017