作者
Eleanor F Harrison, Rachel H Haines, Fiona Cowdell, Tracey H Sach, Taraneh Dean, Ian Pollock, Nigel P Burrows, Hannah Buckley, Jonathan Batchelor, Hywel C Williams, Sandra Lawton, Sara J Brown, Lucy E Bradshaw, Amina Ahmed, Alan A Montgomery, Eleanor J Mitchell, Kim S Thomas
发表日期
2015/12/1
期刊
Trials
卷号
16
期号
1
页码范围
390
出版商
BioMed Central
简介
Background
Eczema is a chronic, itchy skin condition that can have a large impact on the quality of life of patients and their families. People with eczema are often keen to try out non-pharmacological therapies like silk therapeutic garments that could reduce itching or the damage caused by scratching. However, the effectiveness and cost-effectiveness of these garments in the management of eczema has yet to be proven. The CLOTHES Trial will test the hypothesis that ‘silk therapeutic garments plus standard eczema care’ is superior to ‘standard care alone’ for children with moderate to severe eczema.
Methods/Design
Parallel group, observer-blind, pragmatic, multi-centre randomised controlled trial of 6 months’ duration.
Three hundred children aged 1 to 15 years with moderate to severe eczema will be randomised (1:1) to receive silk …
学术搜索中的文章
EF Harrison, RH Haines, F Cowdell, TH Sach, T Dean… - Trials, 2015