作者
Neil N Patel, Ivy W Maina, Edward C Kuan, Vasiliki Triantafillou, Michal A Trope, Ryan M Carey, Alan D Workman, Charles C Tong, Michael A Kohanski, James N Palmer, Nithin D Adappa, Jason G Newman, Jason A Brant
发表日期
2020/12
来源
Journal of Neurological Surgery Part B: Skull Base
卷号
81
期号
06
页码范围
701-708
出版商
Georg Thieme Verlag KG
简介
Background Sinonasal adenocarcinoma (SNAC) is a rare malignancy arising from mucus-secreting glandular tissue. Limited large-scale studies are available due to its rarity. We evaluated SNAC in the National Cancer Database (NCDB), a source that affords multi-institutional, population studies of rare cancers and their outcomes.
Methods The NCDB was queried for adenocarcinoma in the sinonasal tract. Multivariate analyses were performed to evaluate for factors contributing to overall survival (OS).
Results A total of 553 patients were identified. The cohort was composed of 59.3% males. The nasal cavity was the most common primary site, representing 44.1% of cases. About 5.7% of patients presented with nodal disease, while 3.3% had distant metastases. About 40.6% of cases presented with stage IV disease. About 73.5% of patients underwent surgery, 54.2% received radiation therapy, and 27.7 …
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NN Patel, IW Maina, EC Kuan, V Triantafillou… - Journal of Neurological Surgery Part B: Skull Base, 2020