作者
Omkar Indari, Annu Rani, Budhadev Baral, Süleyman Ergün, Kiran Bala, Srikanth Karnati, Hem Chandra Jha
发表日期
2023/1/1
期刊
Microbial Pathogenesis
卷号
174
页码范围
105946
出版商
Academic Press
简介
Viruses utilize clever strategies of interacting with various cellular factors, to remodel an organelle function, for the establishment of successful infection. In recent decades, numerous studies revealed the exploitation of the peroxisomal compartment by viruses. Epstein-Barr virus (EBV) is a ubiquitous virus linked with various cancers and neurological disorders. Till now, there is no report regarding the impacts of EBV infection on peroxisomal compartment. Therefore, we investigate the modulation of peroxisomal proteins in EBV transformed cell lines and during acute EBV infection. EBV positive Burkitt lymphoma cells of different origins as EBV transformed cells along with EBV negative Burkitt lymphoma cells as a control were used in this study. For acute EBV infection experiments, we infected peripheral blood mononuclear cells with EBV for three days. Thereafter, analyzed the gene expression patterns of …
引用总数
学术搜索中的文章
O Indari, A Rani, B Baral, S Ergün, K Bala, S Karnati… - Microbial Pathogenesis, 2023