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ContextPatients with unstable angina or non–ST-segment elevation myocardial infarction (NSTEMI) can be cared for with a routine invasive strategy involving coronary angiography and revascularization or more conservatively with a selective invasive strategy in which only those with recurrent or inducible ischemia are referred for acute intervention.ObjectiveTo conduct a meta-analysis that compares benefits and risks of routine invasive vs selective invasive strategies.Data SourcesRandomized controlled trials identified through search of MEDLINE and the Cochrane databases (1970 through June 2004) and hand searching of cross-references from original articles and reviews.Study SelectionTrials were included that involved patients with unstable angina or NSTEMI who received a routine invasive or a selective invasive strategy.Data ExtractionMajor outcomes of death and myocardial infarction (MI) occurring …