作者
Michelle O’Donoghue, William E Boden, Eugene Braunwald, Christopher P Cannon, Tim C Clayton, Robbert J de Winter, Keith AA Fox, Bo Lagerqvist, Peter A McCullough, Sabina A Murphy, Rudolf Spacek, Eva Swahn, Lars Wallentin, Fons Windhausen, Marc S Sabatine
发表日期
2008/7/2
期刊
Jama
卷号
300
期号
1
页码范围
71-80
出版商
American Medical Association
简介
Context
Although an invasive strategy is frequently used in patients with non–ST-segment elevation acute coronary syndromes (NSTE ACS), data from some trials suggest that this strategy may not benefit women.
Objective
To conduct a meta-analysis of randomized trials to compare the effects of an invasive vs conservative strategy in women and men with NSTE ACS.
Data Sources
Trials were identified through a computerized literature search of the MEDLINE and Cochrane databases (1970-April 2008) using the search terms invasive strategy, conservative strategy, selective invasive strategy, acute coronary syndromes, non-ST-elevation myocardial infarction, and unstable angina.
Study Selection
Randomized clinical trials comparing an invasive vs conservative treatment strategy in patients with NSTE ACS.
Data Extraction
The principal investigators for each trial provided the sex-specific incidences of death …
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