作者
Stephanie PB Caligiuri, Brian Penner, Grant N Pierce
发表日期
2014/6/18
期刊
Trials
卷号
15
期号
1
页码范围
232
出版商
BioMed Central Ltd
简介
Background
In 2013 the World Health Organization deemed hypertension as a global crisis as it is the leading risk factor attributed to global mortality. Therefore, there is a great need for effective alternative treatment strategies to combat a condition that affects 40% of adults worldwide. Recently, the FlaxPAD Trial observed a significant reduction in systolic and diastolic blood pressure in hypertensive patients with peripheral arterial disease that consumed 30 g of milled flaxseed per day for one year. However, these patients were already on anti-hypertensive medication. Therefore, there is a need to assess if dietary flaxseed can effectively reduce blood pressure in the absence of peripheral arterial disease and anti-hypertensive medication in newly diagnosed hypertensive patients.
Methods/Design
The HYPERFlax Trial is a parallel, superiority, phase II/III …
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