作者
Esther M Crawley, Daisy M Gaunt, Kirsty Garfield, William Hollingworth, Jonathan AC Sterne, Lucy Beasant, Simon M Collin, Nicola Mills, Alan A Montgomery
发表日期
2018/2/1
期刊
Archives of disease in childhood
卷号
103
期号
2
页码范围
155-164
出版商
BMJ Publishing Group Ltd
简介
Objective
Investigate the effectiveness and cost-effectiveness of the Lightning Process (LP) in addition to specialist medical care (SMC) compared with SMC alone, for children with chronic fatigue syndrome/myalgic encephalitis (CFS/ME).
Design
Pragmatic randomised controlled open trial. Participants were randomly assigned to SMC, or SMC plus the LP (SMC+LP). Randomisation was minimised by age and gender.
Setting
Specialist paediatric CFS/ME service.
Patients
Aged 12–18 years with mild/moderate CFS/ME.
Main outcome measures
The primary outcome was the SF-36 physical function subscale (PFS) at 6 months. Secondary outcomes included the SF-36-PFS at 3 and 12 months, and pain, anxiety, depression, school attendance and cost-effectiveness from a health service perspective at 3, 6 and 12 months.
Results
We recruited 100 participants between September 2010 and September 2013. We tested …
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