作者
Leila Rooshenas, Lauren J Scott, Jane M Blazeby, Chris A Rogers, Kate M Tilling, Samantha Husbands, Carmel Conefrey, Nicola Mills, Robert C Stein, Chris Metcalfe, Andrew J Carr, David J Beard, Tim Davis, Sangeetha Paramasivan, Marcus Jepson, Kerry Avery, Daisy Elliott, Caroline Wilson, Jenny L Donovan, Robert Andrews, James Byrne, Jamie Kelly, Graziella Mazza, David Mahon, Hamish Noble, Barnaby C Reeves, Janice L Thompson, Sarah Wordsworth, Richard Welbourn, David Beard, Andrew Carr, Jonathan Cook, Cushla Cooper, Benjamin Dean, Alastair Gray, Stephen Gwilym, Andrew Judge, Naomi Merritt, Jane Moser, Jonathan Rees, Ines Rombach, Julian Savulescu, Irene Tracey, Karolina Wartolowska, Eleanor Harrison, Wei Tan, Alexia Karantana, Kirsty Sprange, Lelia Duley, William Hollingworth, Alan A Montgomery, Rob Stein, John Bartlett, David Cameron, Amy Campbell, Peter Canney, Janet Dunn, Helena Earl, Mary Falzon, Adele Francis, Peter Hall, Victoria Harmer, Helen Higgins, Louise Hiller, Luke Hughes-Davies, Claire Hulme, Iain Macpherson, Andreas Makris, Andrea Marshall, Christopher McCabe, Adrienne Morgan, Sarah Pinder, Christopher Poole, Elena Provenzano, Daniel Rea, Nigel Stallard, Kerry NL Avery, C Paul Barham, Richard Berrisford, Jackie Elliott, Stephen J Falk, Rob Goldin, George Hanna, Andrew A Hollowood, Richard Krysztopik, Sian Noble, Grant Sanders, Christopher G Streets, Dan R Titcomb, Tim Wheatley
发表日期
2019/2/1
期刊
Journal of clinical epidemiology
卷号
106
页码范围
108-120
出版商
Pergamon
简介
Objective
To evaluate the impact of the QuinteT Recruitment Intervention (QRI) on recruitment in challenging randomized controlled trials (RCTs) that have applied the intervention. The QRI aims to understand recruitment difficulties and then implements “QRI actions” to address these as recruitment proceeds.
Study Design and Setting
A mixed-methods study, comprising (1) before-and-after comparisons of recruitment rates and the numbers of patients approached and (2) qualitative case studies, including documentary analysis and interviews with RCT investigators.
Results
Five UK-based publicly funded RCTs were included in the evaluation. All recruited to target. Randomized controlled trial 2 and RCT 5 both received up-front prerecruitment training before the intervention was applied. Randomized controlled trial 2 did not encounter recruitment issues and recruited above target from its outset. Recruitment …
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L Rooshenas, LJ Scott, JM Blazeby, CA Rogers… - Journal of clinical epidemiology, 2019