作者
Luis Calzadilla‐Bertot, Gary P Jeffrey, Bryon Jacques, Geoffrey McCaughan, Michael Crawford, Peter Angus, Robert Jones, Edward Gane, Stephen Munn, Graeme Macdonald, Jonathan Fawcett, Alan Wigg, John Chen, Michael Fink, Leon A Adams
发表日期
2019/1
期刊
Liver transplantation
卷号
25
期号
1
页码范围
25-34
简介
The worldwide increase in obesity and diabetes has led to predictions that nonalcoholic steatohepatitis (NASH) will become the leading indication for orthotopic liver transplantation (OLT). Data supporting this prediction from outside the United States are limited. Thus, we aimed to determine trends in the frequency of NASH among adults listed and undergoing OLT in Australia and New Zealand (ANZ) from 1994 to 2017. Data from the ANZ Liver Transplant Registry were analyzed with patients listed for fulminant liver failure, retransplantation, or multivisceral transplants excluded. Nonparametric trend, Spearman rank correlation, and regression analysis were used to assess trends in etiologies of liver disease over time. Of 5016 patient wait‐list registrants, a total of 3470 received an OLT. The percentage of patients with NASH activated for OLT increased significantly from 2.0% in 2003 to 10.9% in 2017 (trend …
引用总数
20192020202120222023202431571465