作者
Beth A Malow
发表日期
2005/11/1
来源
Neurologic clinics
卷号
23
期号
4
页码范围
1127-1147
出版商
Elsevier
简介
Since Aristotle and Hippocrates noted the occurrence of epileptic seizures during sleep, the relationship between sleep and epilepsy has intrigued physicians and researchers. In the late nineteenth century, Gowers [1] commented on the relationship of seizures to the sleep-wake cycle. In 1929, Langdon-Down and Brain [2] observed that nocturnal seizures peaked approximately 2 hours after bedtime and between 4 AM and 5 AM, whereas daytime seizures were most prevalent in the first hour after waking. Berger’s discovery of the electroencephalogram (EEG) in the 1920s provided a diagnostic tool for studies researching the interrelationship of sleep and epilepsy [3]. Gibbs and Gibbs [4] demonstrated that interictal epileptiform discharges were activated by sleep, and obtaining sleep during an EEG recording remains a standard activating procedure today. Janz [5] differentiated awakening, nocturnal, and diurnal …
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