作者
Dina Labib, Alessandro Satriano, Steven Dykstra, Reis Hansen, Yoko Mikami, David G Guzzardi, Zdenka Slavikova, Patricia Feuchter, Jacqueline Flewitt, Sandra Rivest, Rosa Sandonato, Carmen P Lydell, Andrew G Howarth, Louis Kolman, Brian Clarke, D Ian Paterson, Gavin Y Oudit, Edith Pituskin, Winson Y Cheung, Joon Lee, James A White
发表日期
2021/5/4
期刊
Journal of the American Heart Association
卷号
10
期号
9
页码范围
e019811
简介
Background
The overlap between cancer and cardiovascular care continues to expand, with intersections emerging before, during, and following cancer therapies. To date, emphasis has been placed on how cancer therapeutics influence downstream cardiac health. However, whether active malignancy itself influences chamber volumes, function, or overall myocardial tissue health remains uncertain. We sought to perform a comprehensive cardiovascular magnetic resonance‐based evaluation of cardiac health in patients with chemotherapy‐naïve cancer with comparison with a healthy volunteer population.
Methods and Results
Three‐hundred and eighty‐one patients with active breast cancer or lymphoma before cardiotoxic chemotherapy exposure were recruited in addition to 102 healthy volunteers. Both cohorts underwent standardized cardiovascular magnetic resonance imaging with quantification of …
学术搜索中的文章
D Labib, A Satriano, S Dykstra, R Hansen, Y Mikami… - Journal of the American Heart Association, 2021