作者
D Labib, S Dykstra, A Satriano, Y Mikami, E Prosia, J Flewitt, AG Howarth, CP Lydell, L Kolman, DI Paterson, GY Oudit, E Pituskin, WY Cheung, J Lee, JA White
发表日期
2021/10/1
期刊
European Heart Journal
卷号
42
期号
Supplement_1
页码范围
ehab724. 2878
出版商
Oxford University Press
简介
Background
Right ventricular (RV) function has an established incremental prognostic value in cardiomyopathy. Studies on cancer therapeutics-related cardiac dysfunction (CTRCD) primarily focused on the left ventricle (LV), with conflicting results from small studies dedicated to RV dysfunction.
Purpose
We sought to investigate the influence of chemotherapy on RV function relative to LV function using serial cardiac magnetic resonance (CMR).
Methods
Patients were enrolled as part of Cardiotoxicity Prevention Research Initiative (CAPRI) Registry aimed at evaluating CMR-based markers for surveillance of CTRCD. Patients underwent non-contrast CMR imaging prior to initiation of anthracyclines and/or trastuzumab and serially every 3 months during the first year, then annually thereafter. We included patients who had a baseline and ≥1 follow-up scan …
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D Labib, S Dykstra, A Satriano, Y Mikami, E Prosia… - European Heart Journal, 2021