作者
Yu Wang, Igor V Tetko, Mark A Hall, Eibe Frank, Axel Facius, Klaus FX Mayer, Hans W Mewes
发表日期
2005/2/1
期刊
Computational biology and chemistry
卷号
29
期号
1
页码范围
37-46
出版商
Elsevier
简介
A DNA microarray can track the expression levels of thousands of genes simultaneously. Previous research has demonstrated that this technology can be useful in the classification of cancers. Cancer microarray data normally contains a small number of samples which have a large number of gene expression levels as features. To select relevant genes involved in different types of cancer remains a challenge. In order to extract useful gene information from cancer microarray data and reduce dimensionality, feature selection algorithms were systematically investigated in this study. Using a correlation-based feature selector combined with machine learning algorithms such as decision trees, nave Bayes and support vector machines, we show that classification performance at least as good as published results can be obtained on acute leukemia and diffuse large B-cell lymphoma microarray data sets. We also …
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