作者
Oscar L Lopez, William J Jagust, Corinne Dulberg, James T Becker, Steven T DeKosky, Annette Fitzpatrick, John Breitner, Constantine Lyketsos, Beverly Jones, Claudia Kawas, Michelle Carlson, Lewis H Kuller
发表日期
2003/10/1
期刊
Archives of neurology
卷号
60
期号
10
页码范围
1394-1399
出版商
American Medical Association
简介
Objective
To examine the risk factors for mild cognitive impairment (MCI) in a longitudinal population study—the Cardiovascular Health Study Cognition Study.
Design
We examined the factors that in the period 1991 through 1994 predicted the development of MCI in all participants of the Cardiovascular Health Study Cognition Study. Further examination was conducted in the Pittsburgh, Pa, cohort (n = 927), where participants with MCI were classified as having either the MCI amnestic-type or the MCI multiple cognitive deficits–type.
Setting
Multicenter population study.
Patients
This study includes all participants of the Cardiovascular Health Study Cognition Study (n = 3608) who had a magnetic resonance imaging (MRI) scan of the brain between 1991 and 1994, and detailed neuropsychological, neurological, and medical evaluations to identify the presence of MCI or dementia in the period 1998 to 1999. The mean …
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OL Lopez, WJ Jagust, C Dulberg, JT Becker… - Archives of neurology, 2003