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To develop a previously reported, electrocardiogram (ECG)‐gated, motion‐resolved 5D compressed sensing whole‐heart sparse MRI methodology into an automated, optimized, and fully self‐gated free‐running framework in which external gating or triggering devices are no longer needed.

Cardiac and respiratory self‐gating signals were extracted from raw image data acquired in 12 healthy adult volunteers with a non‐ECG‐triggered 3D radial golden‐angle 1.5 T balanced SSFP sequence. To extract cardiac self‐gating signals, central k‐space coefficient signal analysis (k₀ modulation), as well as independent and principal component analyses were performed on selected k‐space profiles. The procedure yielding triggers with the smallest deviation from those of the reference ECG was selected for the automated protocol. Thus, optimized cardiac and respiratory self‐gating signals were used …