作者
Andreas Reisner, Karen A Krogfelt, Bjarke M Klein, Ellen L Zechner, Søren Molin
发表日期
2006/5/15
期刊
Journal of bacteriology
卷号
188
期号
10
页码范围
3572-3581
出版商
American Society for Microbiology
简介
Our understanding of Escherichia coli biofilm formation in vitro is based on studies of laboratory K-12 strains grown in standard media. However, pathogenic E. coli isolates differ substantially in their genetic repertoire from E. coli K-12 and are subject to heterogeneous environmental conditions. In this study, in vitro biofilm formation of 331 nondomesticated E. coli strains isolated from healthy (n = 105) and diarrhea-afflicted children (n = 68), bacteremia patients (n = 90), and male patients with urinary tract infections (n = 68) was monitored using a variety of growth conditions and compared to in vitro biofilm formation of prototypic pathogenic and laboratory strains. Our results revealed remarkable variation among the capacities of diverse E. coli isolates to form biofilms in vitro. Notably, we could not identify an association of increased biofilm formation in vitro with a specific strain collection that represented pathogenic E …
引用总数
学术搜索中的文章
A Reisner, KA Krogfelt, BM Klein, EL Zechner, S Molin - Journal of bacteriology, 2006