作者
Karthiga Durairaj, Barsha Roy, Natarajan Chandrasekaran, Suresh Palamadai Krishnan, Amitava Mukherjee
发表日期
2020/4
期刊
IET nanobiotechnology
卷号
14
期号
2
页码范围
161-166
出版商
The Institution of Engineering and Technology
简介
The production of different size and shape silver nanoparticles (AgNPs) has increased considerably in recent years due to several commercial and biological applications. Here, rod‐shaped AgNPs (SNRs) were prepared using the microwave‐assisted method and characterised by ultraviolet–visible spectroscopy, and transmission electron microscopy analysis. The present study aims to investigate the cyto–genotoxic effect of various concentrations (5, 10, and 15 µM) of SNRs using Allium cepa model. As a result, concentration‐dependent cyto–genotoxic effect of SNRs was observed through a decrease in the mitotic index, and an increase in the chromosomal aberrations such as chromosome break, disturbed metaphase, and anaphase bridge. To check the impact of Ag+ ions, 15 µM silver nitrate (AgNO3) was prepared and tested in all the assays. Furthermore, cell viability and different reactive oxygen species …
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K Durairaj, B Roy, N Chandrasekaran, SP Krishnan… - IET nanobiotechnology, 2020