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Objective:

The impact on mood and memory of consuming a probiotic containing milk drink, or a placebo, was examined as, previously, a poor mood has been found to correlate with the frequency of constipation.

Design:

A double-blind placebo-controlled trial with random allocation of subjects.

Setting:

Subjects went about their normal life in the community apart from three visits to the laboratory.

Subjects:

One hundred and thirty-two healthy members of general population, mean age 61.8 years, volunteered in response to local media coverage. One hundred and twenty-four finished the trial.

Intervention:

For a 3-week period, either a probiotic containing milk drink, or a placebo, were consumed daily. Mood and cognition were measured at baseline, and after 10 and 20 days of consumption.

Results:

At baseline those who reported themselves to be less frequently constipated were more clearheaded, confident and elated …