作者
James L Devin, Michelle M Hill, Marina Mourtzakis, Joe Quadrilatero, David G Jenkins, Tina L Skinner
发表日期
2019/4
期刊
The Journal of physiology
卷号
597
期号
8
页码范围
2177-2184
简介
Key points
- Physical activity is associated with reduced mortality rates for survivors of colorectal cancer.
- Acute high intensity interval exercise (HIIE) reduced colon cancer cell number in vitro and promoted increases in inflammatory cytokines immediately following exercise.
- This acute suppression of colon cancer cell number was transient and not observed at 120 minutes post-acute HIIE.
- The acute effects of exercise may constitute an important mechanism by which exercise can influence colorectal cancer outcomes.
Abstract
Physical activity is associated with significant reductions in colorectal cancer mortality. However, the mechanisms by which exercise mediates this anti‐oncogenic effect are not clear. In the present study, colorectal cancer survivors completed acute (n = 10) or chronic (n = 10) exercise regimes. An acute high intensity interval exercise session (HIIE; 4 × 4 min at 85–95% peak heart rate) was …
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JL Devin, MM Hill, M Mourtzakis, J Quadrilatero… - The Journal of physiology, 2019