作者
Shufa Zheng, Jian Fan, Fei Yu, Baihuan Feng, Bin Lou, Qianda Zou, Guoliang Xie, Sha Lin, Ruonan Wang, Xianzhi Yang, Weizhen Chen, Qi Wang, Dan Zhang, Yanchao Liu, Renjie Gong, Zhaohui Ma, Siming Lu, Yanyan Xiao, Yaxi Gu, Jinming Zhang, Hangping Yao, Kaijin Xu, Xiaoyang Lu, Guoqing Wei, Jianying Zhou, Qiang Fang, Hongliu Cai, Yunqing Qiu, Jifang Sheng, Yu Chen, Tingbo Liang
发表日期
2020/4/21
期刊
bmj
卷号
369
出版商
British Medical Journal Publishing Group
简介
Objective
To evaluate viral loads at different stages of disease progression in patients infected with the 2019 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the first four months of the epidemic in Zhejiang province, China.
Design
Retrospective cohort study.
Setting
A designated hospital for patients with covid-19 in Zhejiang province, China.
Participants
96 consecutively admitted patients with laboratory confirmed SARS-CoV-2 infection: 22 with mild disease and 74 with severe disease. Data were collected from 19 January 2020 to 20 March 2020.
Main outcome measures
Ribonucleic acid (RNA) viral load measured in respiratory, stool, serum, and urine samples. Cycle threshold values, a measure of nucleic acid concentration, were plotted onto the standard curve constructed on the basis of the standard product. Epidemiological, clinical, and laboratory characteristics and treatment and …
学术搜索中的文章
S Zheng, J Fan, F Yu, B Feng, B Lou, Q Zou, G Xie… - bmj, 2020