作者
Rebecca M May, Clarissa Cassol, Andrew Hannoudi, Christopher P Larsen, Edgar V Lerma, Randy S Haun, Juarez R Braga, Samar I Hassen, Jon Wilson, Christine VanBeek, Mahesha Vankalakunti, Lilli Barnum, Patrick D Walker, T David Bourne, Nidia C Messias, Josephine M Ambruzs, Christie L Boils, Shree S Sharma, L Nicholas Cossey, Pravir V Baxi, Matthew Palmer, Jonathan E Zuckerman, Vighnesh Walavalkar, Anatoly Urisman, Alexander J Gallan, Laith F Al-Rabadi, Roger Rodby, Valerie Luyckx, Gustavo Espino, Srivilliputtur Santhana-Krishnan, Brent Alper, Son G Lam, Ghadeer N Hannoudi, Dwight Matthew, Mark Belz, Gary Singer, Srikanth Kunaparaju, Deborah Price, Saurabh Chawla, Chetana Rondla, Mazen A Abdalla, Marcus L Britton, Subir Paul, Uday Ranjit, Prasad Bichu, Sean R Williamson, Yuvraj Sharma, Ariana Gaspert, Philipp Grosse, Ian Meyer, Brahm Vasudev, Mohamad El Kassem, Juan Carlos Q Velez, Tiffany N Caza
发表日期
2021/12/1
期刊
Kidney international
卷号
100
期号
6
页码范围
1303-1315
出版商
Elsevier
简介
Kidney failure is common in patients with Coronavirus Disease-19 (COVID-19), resulting in increased morbidity and mortality. In an international collaboration, 284 kidney biopsies were evaluated to improve understanding of kidney disease in COVID-19. Diagnoses were compared to five years of 63,575 native biopsies prior to the pandemic and 13,955 allograft biopsies to identify diseases that have increased in patients with COVID-19. Genotyping for APOL1 G1 and G2 alleles was performed in 107 African American and Hispanic patients. Immunohistochemistry for SARS-CoV-2 was utilized to assess direct viral infection in 273 cases along with clinical information at the time of biopsy. The leading indication for native biopsy was acute kidney injury (45.4%), followed by proteinuria with or without concurrent acute kidney injury (42.6%). There were more African American patients (44.6%) than patients of other …
学术搜索中的文章
RM May, C Cassol, A Hannoudi, CP Larsen, EV Lerma… - Kidney international, 2021