作者
Felice Giuliante, Francesco Ardito, Maria Vellone, Giuseppina Ranucci, Bruno Federico, Ivo Giovannini, Gennaro Nuzzo
发表日期
2009/12/1
期刊
Journal of surgical oncology
卷号
100
期号
7
页码范围
538-545
出版商
Wiley Subscription Services, Inc., A Wiley Company
简介
Background and Objectives
Survival analyses after hepatectomy for colorectal liver metastases (CRLM) mostly address tumorrelated factors; this study has simultaneously evaluated interventional factors which may be influenced by the surgeon.
Methods
Operative and longterm results of 251 consecutive patients undergoing hepatectomy for CRLM between 1992 and 2007 were analyzed.
Results
Mortality was 0.8%, morbidity 22.9%, intraoperative blood transfusion rate 23.1% (19.4% with pedicle clamping, 35.0% without clamping, P = 0.01), R0resection 93.6% (2/3 with tumorfree margin >5 mm). The 3, 5, 10year overall and diseasefree survival rates were 55.2%, 38.9%, 24.2%, and 37.1%, 28.2%, 25.4%. Univariate analysis: lower survival was related to transfusion requirement, tumor size >5 cm, tumorfree margin ≤5 mm, major hepatectomy, R1resection, multiplicity of CRLM, preoperative …
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