作者
Felice Giuliante, Francesco Ardito, Alessandro Ferrero, Luca Aldrighetti, Giorgio Ercolani, Gennaro Grande, Francesca Ratti, Ivo Giovannini, Bruno Federico, Antonio D Pinna, Lorenzo Capussotti, Gennaro Nuzzo
发表日期
2014/8/1
期刊
Journal of the American College of Surgeons
卷号
219
期号
2
页码范围
285-294
出版商
No longer published by Elsevier
简介
Background
We aimed to evaluate the feasibility and long-term results of 2-stage hepatectomy (TSH) in patients with bilobar colorectal liver metastases (CRLM).
Study Design
We performed a retrospective multicenter study including 4 Italian hepatobiliary surgery units. One hundred thirty patients were selected for TSH between 2002 and 2011. The primary endpoint was feasibility of TSH and analysis of factors associated with failure to complete the procedure. The secondary endpoint was the long-term survival analysis.
Results
Patients presented with synchronous CRLM in 80.8% of cases, with a mean number of 8.3 CRLM and with concomitant extrahepatic disease in 20.0% of cases. The rate of failure to complete TSH was 21.5% and tumor progression was the most frequent reason for failure (18.5% of cases). Primary tumor characteristics, type, number, and distribution of CRLM were not associated with …
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F Giuliante, F Ardito, A Ferrero, L Aldrighetti, G Ercolani… - Journal of the American College of Surgeons, 2014
