作者
K Carlos El-Tallawi, Danai Kitkungvan, Jiaqiong Xu, Vittorio Cristini, Eric Y Yang, Miguel A Quinones, Gerald M Lawrie, William A Zoghbi, Dipan J Shah
发表日期
2021/3/1
期刊
Cardiovascular Imaging
卷号
14
期号
3
页码范围
573-584
出版商
American College of Cardiology Foundation
简介
Objectives
This study hypothesized that left ventricular (LV) enlargement in Barlow disease can be explained by accounting for the total volume load that consists of transvalvular mitral regurgitation (MR) and the prolapse volume.
Background
Barlow disease is characterized by long prolapsing mitral leaflets that can harbor a significant amount of blood—the prolapse volume—at end-systole. The LV in Barlow disease can be disproportionately enlarged relative to MR severity, leading to speculation of Barlow cardiomyopathy.
Methods
Cardiac magnetic resonance (CMR) was used to compare MR, prolapse volume, and heart chambers remodeling in patients with Barlow disease (bileaflet prolapse [BLP]) and in single leaflet prolapse (SLP).
Results
A total of 157 patients (81 with BLP, 76 with SLP) were included. Patients with SLP were older and more had hypertension. Patients with BLP had more heart failure …
学术搜索中的文章
KC El-Tallawi, D Kitkungvan, J Xu, V Cristini, EY Yang… - Cardiovascular Imaging, 2021