作者
Lamiae Grimaldi-Bensouda, Frederic Rouillon, Bernard Astruc, Michel Rossignol, Jacques Benichou, Bruno Falissard, Frederic Limosin, Beatrice Beaufils, Guillaume Vaiva, Helene Verdoux, Yola Moride, Alban Fabre, Florence Thibaut, Lucien Abenhaim, CGS Study Group
发表日期
2012/2/1
期刊
Schizophrenia Research
卷号
134
期号
2-3
页码范围
187-194
出版商
Elsevier
简介
OBJECTIVE
The primary aim of this study was to compare the impact of risperidone long-acting injectable (R-LAI) to other antipsychotics on rates of hospitalisation in real-life settings.
METHOD
The Cohort for the General study of Schizophrenia (CGS) followed 1859 patients diagnosed with schizophrenia (DSM-IV) from 177 psychiatric wards of public and private hospitals across France over a mean period of 12months. These patients were ambulatory or had been hospitalised for less than 93days at study entry. Recruitment was stratified for long-acting second-generation antipsychotic use. A multivariate Poisson regression adjusted for confounding with propensity scores and allowing for autocorrelation was used for the calculation of relative rates of hospitalisation with 95% confidence intervals.
RESULTS
The mean age of participants was 37.65years, 68.3% were male and 36.7% were hospitalised for less than …
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L Grimaldi-Bensouda, F Rouillon, B Astruc… - Schizophrenia Research, 2012