作者
Glenn Hernandez, E Christiaan Boerma, Arnaldo Dubin, Alejandro Bruhn, Matty Koopmans, Vanina Kanoore Edul, Carolina Ruiz, Ricardo Castro, Mario Omar Pozo, Cesar Pedreros, Enrique Veas, Andrea Fuentealba, Eduardo Kattan, Maximiliano Rovegno, Can Ince
发表日期
2013/8/1
期刊
Journal of critical care
卷号
28
期号
4
页码范围
538. e9-538. e14
出版商
WB Saunders
简介
Purpose
The aims of this study are to determine the general relationship of perfused vessel density (PVD) to mortality and organ dysfunctions and to explore if patients in the lowest quartile of distribution for this parameter present a higher risk of bad outcome and to identify systemic hemodynamic and perfusion variables that enhances the probability of finding a severe underlying microvascular dysfunction.
Materials and Methods
This is a retrospective multicenter study including 122 septic shock patients participating in 7 prospective clinical trials on which at least 1 sublingual microcirculatory assessment was performed during early resuscitation.
Results
Perfused vessel density was significantly related to organ dysfunctions and mortality, but this effect was largely explained by patients in the lowest quartile of distribution for PVD (P = .037 [odds ratio {OR}, 8.7; 95% confidence interval {CI}, 1.14-66.78] for mortality …
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G Hernandez, EC Boerma, A Dubin, A Bruhn… - Journal of critical care, 2013