作者
Arnaldo Dubin, Gastón Murias, Elisa Estenssoro, Héctor Canales, Pablo Sottile, Julio Badie, Marcelo Barán, Silvio Rossi, Mercedes Laporte, Fernando Pálizas, Jorge Giampieri, Diego Mediavilla, Esteban Vacca, Diego Botta
发表日期
2000/11
期刊
Intensive care medicine
卷号
26
页码范围
1619-1623
出版商
Springer-Verlag
简介
Objectives: To examine the relationship between end-tidal CO2 (PETCO2) and its physiological determinants, pulmonary blood flow (cardiac output, CO) and CO2 production (VCO2), in a model of hemorrhagic shock during fixed minute ventilation.
Design and setting: Prospective, observational study in a research laboratory at a university center.
Subjects and interventions: Six anesthetized, intubated, and mechanically ventilated mongrel dogs. Progressive stepwise bleeding.
Measurements and results: We continuously measured PETCO2 with a capnograph, pulmonary artery blood flow with an electromagnetic flow probe, arterial oxygen saturation (SaO2) with a fiberoptic catheter, and oxygen consumption (VO2) and VCO2 by expired gases analysis. Oxygen delivery (DO2) was continuously calculated from pulmonary blood flow and SaO2. We …
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A Dubin, G Murias, E Estenssoro, H Canales, P Sottile… - Intensive care medicine, 2000