作者
Elisa Estenssoro, Arnaldo Dubin, Enrique Laffaire, Héctor S Canales, Gabriela Sáenz, Miriam Moseinco, Pierina Bachetti
发表日期
2003/11
期刊
Intensive care medicine
卷号
29
页码范围
1936-1942
出版商
Springer-Verlag
简介
Objective
We examined whether PEEP during the first hours of ARDS can induce such a change in oxygenation that could mask fulfillment of the AECC criteria of a PaO2/FIO2 ≤ 200 essential for ARDS diagnosis.
Design and setting
Observational, prospective cohort in two medical-surgical ICU in teaching hospitals.
Patients
48 consecutive patients who met AECC criteria of ARDS on 0 PEEP (ZEEP) at the moment of diagnosis.
Measurements and results
PaO2/FIO2 and lung mechanics were recorded on admission (0 h) to the ICU on ZEEP, and after 6, 12, and 24 h on PEEP levels selected by attending physicians. Lung Injury Score (LIS) was calculated at 0 and 24 h. PaO2/FIO2 rose significantly from 121±45 on ZEEP at 0 h, to 234±85 on PEEP of 12.8±3.7 cmH2O after 24 h. LIS did not …
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E Estenssoro, A Dubin, E Laffaire, HS Canales… - Intensive care medicine, 2003