作者
Sayyid Hasan, Velma Aho, Pedro Pereira, Lars Paulin, Saila B Koivusalo, Petri Auvinen, Johan G Eriksson
发表日期
2018/1
期刊
Acta obstetricia et gynecologica Scandinavica
卷号
97
期号
1
页码范围
38-46
简介
Introduction
An altered gut microbiome composition is shown to be associated with various diseases and health outcomes. We compare the gut microbiota of women who developed gestational diabetes mellitus (GDM) with that of those who did not, and the gut microbiota of their offspring, to determine any differences in the composition and diversity of their gut microbiota, which may be correlated with their GDM state.
Material and methods
All women were at high risk for GDM and participated in the Finnish Gestational Diabetes Prevention Study (RADIEL). Stool samples were obtained, 5 years postpartum, from 60 GDM‐positive women, 68 non‐GDM control women, and their children (n = 109), 237 individuals in total. 16S ribosomal RNA gene sequencing was employed to determine the composition of bacterial communities present. Statistical correlations were inferred between clinical variables and microbiota …
引用总数
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学术搜索中的文章
S Hasan, V Aho, P Pereira, L Paulin, SB Koivusalo… - Acta obstetricia et gynecologica Scandinavica, 2018