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Naringin, a glycosylated polyphenol of the flavanones class and its aglycone, naringenin, have been shown to possess many health benefits, therefore they show promise for supplementation of staple foods and beverages, as a mean of preventive medicine. Major obstacles to the successful implementation of these flavanones as nutraceuticals are their low water-solubility and the related low oral bioavailability. Naringin is more soluble but is also very bitter. To allow the enrichment of clear beverages with these important health promoters, we have used native and preheated β-Lactoglobulin (β-Lg) based nanovehicles. Using UV spectrophotometry and intrinsic fluorescence methods, we have found that naringenin forms complexes with preheated and non-preheated β-Lg, with K_a in the order of 10⁴ M⁻¹. No binding was found between naringin and β-Lg, probably due to the lower hydrophobicity of naringin and …