作者
Steen Christensen, Ricardo Pérez Dulzaides, Victoria E Hedrick, AJM Zehadee Momtaz, Ernesto S Nakayasu, Lake N Paul, Laura R Serbus
发表日期
2016/9/1
期刊
Applied and Environmental Microbiology
卷号
82
期号
17
页码范围
5354-5363
出版商
American Society for Microbiology
简介
Endosymbiosis is a unique form of interaction between organisms, with one organism dwelling inside the other. One of the most widespread endosymbionts is Wolbachia pipientis, a maternally transmitted bacterium carried by insects, crustaceans, mites, and filarial nematodes. Although candidate proteins that contribute to maternal transmission have been identified, the molecular basis for maternal Wolbachia transmission remains largely unknown. To investigate transmission-related processes in response to Wolbachia infection, ovarian proteomes were analyzed from Wolbachia-infected Drosophila melanogaster and D. simulans. Endogenous and variant host-strain combinations were investigated. Significant and differentially abundant ovarian proteins were detected, indicating substantial regulatory changes in response to Wolbachia. Variant Wolbachia strains were associated with a broader impact on the …
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S Christensen, R Pérez Dulzaides, VE Hedrick… - Applied and Environmental Microbiology, 2016