作者
Joel M Gelfand, Joy Wan, Kristina Callis Duffin, Gerald G Krueger, Robert E Kalb, Jamie D Weisman, Brian R Sperber, Michael B Stierstorfer, Bruce A Brod, Stephen M Schleicher, Bruce F Bebo, Andrea B Troxel, Daniel B Shin, Jane M Steinemann, Jennifer Goldfarb, Howa Yeung, Abby S Van Voorhees
发表日期
2012/4/1
期刊
Archives of dermatology
卷号
148
期号
4
页码范围
487-494
出版商
American Medical Association
简介
Objective
To compare the effectiveness of biologic systemic therapy, nonbiologic systemic therapy, and phototherapy for treatment of psoriasis.
Design
A cross-sectional design was used.
Setting
Ten outpatient dermatology sites across the United States participating in the Dermatology Clinical Effectiveness Research Network contributed to the study.
Participants
A total of 713 patients with plaque psoriasis receiving systemic monotherapy (ie, methotrexate sodium, adalimumab, etanercept, or ustekinumab) or narrowband UV-B phototherapy.
Main Outcome Measures
The primary outcome of the study was clear or almost clear skin on the Physician Global Assessment scale. Secondary outcomes were score on the Psoriasis Area and Severity Index, affected body surface area, and score on the Dermatology Life Quality Index.
Results
The proportion of patients with clear or almost clear ratings on the Physician Global …
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JM Gelfand, J Wan, KC Duffin, GG Krueger, RE Kalb… - Archives of dermatology, 2012