作者
Aaron J Siegler, Farah Mouhanna, Robertino Mera Giler, Kevin Weiss, Elizabeth Pembleton, Jodie Guest, Jeb Jones, Amanda Castel, Howa Yeung, Michael Kramer, Scott McCallister, Patrick S Sullivan
发表日期
2018/12/1
期刊
Annals of epidemiology
卷号
28
期号
12
页码范围
841-849
出版商
Elsevier
简介
Purpose
The number of individuals who have started a regimen for HIV pre-exposure prophylaxis (PrEP) in the United States is not well characterized but has been on the rise since 2012. This analysis assesses the distribution of PrEP use nationally and among subgroups.
Methods
A validated algorithm quantifying tenofovir disoproxil fumarate/emtricitabine for PrEP in the United States was applied to a national prescription database to determine the quarterly prevalence of PrEP use. HIV diagnoses from 2016 were used as an epidemiological proxy for PrEP need. The PrEP-to-need ratio (PnR) was defined as the number of PrEP users divided by new HIV diagnoses.
Results
A total of 70,395 individuals used PrEP in the fourth quarter of 2017: 67,166 males and 3229 females. Nationally, prevalence of PrEP use was 26/100,000 (range across states per 100,000 [RAS/100k]: 4–73) and the PnR was 1.8 (RAS: 0.5–6.6 …
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AJ Siegler, F Mouhanna, RM Giler, K Weiss… - Annals of epidemiology, 2018