作者
Kai En Chan, Cheng Han Ng, Clarissa Elysia Fu, Jingxuan Quek, Gwyneth Kong, Yi Jie Goh, Rebecca Wenling Zeng, Michael Tseng, Manik Aggarwal, Benjamin Nah, Douglas Chee, Zhen Yu Wong, Sitong Zhang, Jiong-Wei Wang, Nicholas WS Chew, Yock Young Dan, Mohammad Shadab Siddiqui, Mazen Noureddin, Arun J Sanyal, Mark Muthiah
发表日期
2023/9/1
期刊
Clinical Gastroenterology and Hepatology
卷号
21
期号
10
页码范围
2560-2569. e15
出版商
WB Saunders
简介
Background
Metabolic associated fatty liver disease (MAFLD) was recently proposed as an alternative name change for better encapsulation of disease. However, there exists a spectrum of MAFLD where both metabolically healthy (MH) and metabolically unhealthy (MU) individuals are included. In view of limited evidence, we sought to examine the prevalence, clinical characteristics, and differences in outcomes of MH-MAFLD at the population level.
Methods
Data were used from the United States National Health and Nutrition Examination Survey 1999 to 2018. Multivariate logistic regression analysis was used to obtain odds ratios for the estimation of events. Survival analysis was conducted with Cox regression and the Fine-Gray subdistribution model.
Results
There were 32,683 overweight and obese individuals included in the analysis. In MAFLD patients, the prevalence of MH-MAFLD was 6.92% (95 …
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